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N-DesMethyl IpratropiuM

endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl (hydroxymethyl)phenylacetate

CAS: 22235-81-0

Molecular Formula: C19H27NO3

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N-DesMethyl IpratropiuM - Names and Identifiers

Name endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl (hydroxymethyl)phenylacetate
Synonyms Ipratropium Impurity E
N-Isopropylnoratropine
N-DesMethyl IpratropiuM
Ipratropium Bromide Impurity 13(Ipratropium EP Impurity E)
endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl (hydroxymethyl)phenylacetate
α-(HydroxyMethyl)benzeneacetic Acid endo-8-(1-Methylethyl)-8- azabicyclo[3.2.1]oct-3-yl Ester
α-(HydroxyMethyl)benzeneacetic Acid endo-8-(1-Methylethyl)-8- azabicyclo[3.2.1]oct-3-yl Ester
α-(HydroxyMethyl)benzeneacetic Acid (3-Endo)-8-(1-Methylethyl)-8-azabicyclo[3.2.1]- oct-3-yl Ester
α-(HydroxyMethyl)benzeneacetic Acid (3-Endo)-8-(1-Methylethyl)-8-azabicyclo[3.2.1]- oct-3-yl Ester
rac-(R*)-α-(Hydroxymethyl)benzeneacetic acid (1R,5S)-8-isopropyl-8-azabicyclo[3.2.1]octane-3α-yl ester
CAS 22235-81-0
EINECS 2448591

N-DesMethyl IpratropiuM - Physico-chemical Properties

Molecular FormulaC19H27NO3
Molar Mass317.42258
Density1.15±0.1 g/cm3(Predicted)
Melting Point112-114°C
Boling Point448.8±45.0 °C(Predicted)
Solubility Chloroform (Slightly), Methanol (Slightly)
AppearanceSolid
ColorWhite to Pale Orange
pKa14.12±0.10(Predicted)
Storage ConditionRefrigerator

N-DesMethyl IpratropiuM - Upstream Downstream Industry

Raw MaterialsNoratropine
endo-8-isopropyl-8-azabicyclo[3.2.1]octan-3-ol
Acetyltropylic chloride
Ethyl phenylacetate
Atropine
Acetone

N-DesMethyl IpratropiuM - Introduction

endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl is an organic compound with the chemical name endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl.

Nature:
endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl is a white crystalline solid, insoluble in water at room temperature, soluble in some organic solvents such as ethanol and Ether solvents. Its structure contains eight-membered heterocyclic ring, in which the nitrogen atom and the hydroxy methyl group on the benzene ring make it have special chemical properties.

Use:
endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl is mainly used in the field of drug research and manufacturing. It is an impurity of the peripheral anticholinergic drug ipratropium bromide. It is used to detect the purity and quality of ipratropium bromide products and perform quality control.

Method:
endo-(±)-8-aza-8-isopropylbicyclo[3.2.1] The preparation method of oct-3-yl (hydroxymethyl)phenylacetate is generally realized by organic synthetic chemical reaction. Specific methods include the synthesis of intermediate compounds followed by specific reaction steps to give the final product.

Safety Information:
Last Update:2024-04-09 02:00:51
N-DesMethyl IpratropiuM
Supplier List
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: N-Isopropylnoratropine Visit Supplier Webpage Request for quotation
CAS: 22235-81-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
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Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: N-Isopropylnoratropine (NINA) Visit Supplier Webpage Request for quotation
CAS: 22235-81-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: N-Isopropylnoratropine Visit Supplier Webpage Request for quotation
CAS: 22235-81-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: N-Isopropylnoratropine (NINA) Visit Supplier Webpage Request for quotation
CAS: 22235-81-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
View History
N-DesMethyl IpratropiuM
卡巴拉汀(利斯的明)中间体 三
CERAMIDE 1 A
Raw Materials for N-DesMethyl IpratropiuM
Noratropine
endo-8-isopropyl-8-azabicyclo[3.2.1]octan-3-ol
Acetyltropylic chloride
Ethyl phenylacetate
Atropine
Acetone
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